Am I in earth, in heaven, or in hell? Sleeping or waking? mad or well-advised? Known unto these, and to myself disguised!
Am I on earth, in heaven, or in hell? Am I sleeping or awake? Am I crazy or thinking clearly? Known to these people, but hidden from myself!
Antipholus of Syracuse · Act 2, Scene 2
After Adriana and Luciana have claimed him as husband and brother-in-law, Antipholus reaches the breaking point of confusion. He does not know if he is awake or dreaming, sane or mad—and crucially, he is known to everyone around him but unknown to himself. The line distills the play's strange logic: that you can only know who you are through the recognition of others.
How comes it now, my husband, O, how comes it, That thou art thus estranged from thyself?
How is it now, my husband, oh, how is it, That you are so distant from yourself?
Adriana · Act 2, Scene 2
Adriana accuses the wrong Antipholus of becoming a stranger to himself, of ceasing to be the man she married. She does not know she is speaking to a literal stranger, but her accusation is metaphysically true: the play asks whether we are still ourselves when no one recognizes us. Her pain about abandonment becomes the play's central philosophical question.
Plead you to me, fair dame? I know you not: In Ephesus I am but two hours old, As strange unto your town as to your talk; Who, every word by all my wit being scann'd, Want wit in all one word to understand.
Are you speaking to me, lady? I don't know you: I've only been in Ephesus for two hours, I'm as unfamiliar with your town as I am with your language; Who, after analyzing every word with all my wit, Can't make sense of even one of them.
Antipholus of Syracuse · Act 2, Scene 2
Antipholus of Syracuse finally speaks, declaring he has been in Ephesus for only two hours and does not know Adriana. His honesty—his genuine claim that he is a stranger—is met with disbelief and interpreted as madness or cruelty. The moment crystallizes the play's cruelty: the truth cannot be heard when everyone is certain of what they know.